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VitaminD3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitaminD. VitaminD3 induces cell differentiation and prevents proliferation of cancer cells.
VitaminD3 octanoate is an octanoate ester of vitaminD3 . VitaminD3 (Cholecalciferol; HY-15398) is a naturally occuring form of vitaminD. VitaminD3 induces cell differentiation and prevents proliferation of cancer cells .
VitaminD3-d7 is the deuterium labeled VitaminD3. VitaminD3 (Cholecalciferol) is a naturally occuring form of vitaminD. VitaminD3 induces cell differentiation and prevents proliferation of cancer cells[1][2].
VitaminD3-d3 is the deuterium labeled VitaminD3. VitaminD3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitaminD. VitaminD3 induces cell differentiation and prevents proliferation of cancer cells.
VitaminD3- 13C3 is the 13C-labeled VitaminD3. VitaminD3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitaminD. VitaminD3 induces cell differentiation and prevents proliferation of cancer cells.
VitaminD3- 13C5 is the deuterium labeled VitaminD3 (HY-15398). VitaminD3 (Cholecalciferol) is a naturally occuring form of vitaminD. VitaminD3 induces cell differentiation and prevents proliferation of cancer cells[1][2].
3-epi-VitaminD3 (Epicholecalciferol) (Compound 4), a VitaminD3 analogue, is a Hedgehog pathway inhibitor with an IC50 of 39.2 μM measured in U87MG cells .
5,6-trans-VitaminD3 (5,6-trans-Cholecalciferol;5,6-trans-Colecalciferol) is a photoproduct of vitaminD3 . VitaminD3 is a naturally occuring form of vitaminD. VitaminD3 induces cell differentiation and prevents proliferation of cancer cells.
3-epi-25-Hydroxy VitaminD3-d6is the deuterium labeled3-epi-25-Hydroxy VitaminD3(HY-142140) . 3-epi-25-Hydroxy VitaminD3 is the vitaminD metabolite, while vitaminD metabolism highly dependent on macrophage polarization. The C3-epimerase pathway for vitaminD is active in macrophages .
Calcifediol-d6 (monohydrate) is the deuterium labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy VitaminD3 monohydrate), a major circulating metabolite of vitaminD3, is a potent VDR ligand .
Ercalcidiol-d3 is the deuterium labeled Ercalcidiol. Ercalcidiol is a metabolite of VitaminsD2. Ercalcidiol can be used as an indicator of vitaminsD status .
Calcifediol- 13C5 (monohydrate) is the 13C-labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy VitaminD3 monohydrate), a major circulating metabolite of vitaminD3, is a potent VDR ligand .
(1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3(1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitaminD receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion .
Pyridoxine-d3 (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride. Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.
Impurity C of Calcitriol, Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) is the hormonally active form of vitaminD, Calcitriol is the active metabolite of vitaminD3 that activates the vitaminD receptor (VDR).
Impurity B of Calcitriol, Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) is the hormonally active form of vitaminD, Calcitriol is the active metabolite of vitaminD3 that activates the vitaminD receptor (VDR).
(24S)-24,25-Dihydroxyvitamin D3 ((24S)-24,25-Dihydroxycholecalciferol) is an inactive form of vitaminD3 which undergoes various levels of hydroxylation to form active vitaminD3 analogs.
Calcitriol Impurities D is the impurity of Calcitriol, Calcitriol is the hormonally active form of vitaminD, Calcitriol is the active metabolite of vitaminD3 that activates the vitaminD receptor (VDR).
Calcitriol Impurities A is the impurity of Calcitriol, Calcitriol is the hormonally active form of vitaminD, Calcitriol is the active metabolite of vitaminD3 that activates the vitaminD receptor (VDR).
1α,25-Dihydroxyprevitamin D3 is the most potent biologically active form of vitaminD3 (VD3). 1α,25-Dihydroxyprevitamin D3 can be used for regulateing calcium absorption .
Calcitriol-d3 is the deuterium labeled Calcitriol[1]. Calcitriol is the most active metabolite of vitaminD and also a vitaminD receptor (VDR) agonist[2][3][4][5].
7-Dehydrocholesterol-d7 is the deuterium labeled 7-Dehydrocholesterol. 7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitaminD3[1][2].
Maxacalcitol-d66 is the deuterated form of Maxacalcitol (22-Oxacalcitriol), which is a non-calcemic vitaminD3 analog and VDR ligand of VDR-like receptors.
Methylmalonic acid-d3 is the deuterium labeled Methylmalonic acid. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer[1][2].
TEI-9648, a VitaminD3 Lactone analogue, is a potent and specific vitaminD receptor (VDR) antagonist. TEI-9648 inhibits VDR/VDRE-mediated genomic actions of 1α,25(OH)2D3. TEI-9648 also inhibits HL-60 cell differentiation induced by of 1α,25(OH)2D3. TEI-9648 has the potential for bone metabolism research .
Isotachysterol 3 is an analog of 1,25-dihydrox VitaminD3. Isotachysterol 3 stimulates intestinal calcium transport and bone calcium mobilization in anephric rats .
L-Tryptophan-d3 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].
Lumisterol 3 (>90%) (9β,10α-Cholesta-5,7-dien-3β-ol) is a normal human secosterooid metabolite from the class of vitaminD3 photoisomer derivatives. Lumisterol 3 (>90%) is used in the preparation of vitaminD .
Thiamine pyrophosphate-d3 is the deuterium labeled Thiamine pyrophosphate. Thiamine pyrophosphate is the coenzyme form of Vitamin B1 and is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex.
7-Dehydrocholesterol (Standard) is the analytical standard of 7-Dehydrocholesterol. This product is intended for research and analytical applications.7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitaminD3.
TEI-9647, a VitaminD3 Lactone analogue, is a potent and specific vitaminD receptor (VDR) antagonist. TEI-9647 inhibits VDR/VDRE-mediated genomic actions of 1α,25(OH)2D3. TEI-9647 inhibits bone resorption and HL-60 cell differentiation induced by of 1α,25(OH)2D3. TEI-9647 has the potential for suppressing the excessive bone resorption and osteoclast formation in Paget's disease .
4-Pyridoxic acid-d3 is the deuterium labeled 4-Pyridoxic acid. 4-Pyridoxic acid is a catabolic product of vitamin B6 which is excreted in the urine[1][2].
Maxacalcitol (22-Oxacalcitriol), a vitaminD3 (HY-15398) analog, is an orally active VDR agonist. Maxacalcitol has a limited calcemic effect. Maxacalcitol has the potential for psoriasis and hyperparathyroidism research .
Inecalcitol (TX 522), a unique vitaminD3 analog, is an orally active vitaminD receptor (VDR) agonist with a Kd of 0.53 nM. Inecalcitol can induce cell apoptosis and has potent anticancer activities . Inecalcitol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Secalciferol ((24R)-24,25-Dihydroxyvitamin D3) is the major active metabolite of VitaminD. Secalciferol is involved in a wide range of biological functions such as calcium homeostasis, cellular differentiation and proliferation processes, as well as other functions related to the immune system .
Eldecalcitol (ED-71) is an orally active vitaminD3 analogue, inhibits bone resorption and increases bone mineral density. Eldecalcitol (ED-71) displays anti-tumor effect and inhibits cell proliferation, migration and induces apoptosis by suppressing GPx-1 .
β-Tocopherol-d3 is the deuterium labeled β-Tocopherol. β-Tocopherol is an analogue of vitamin E, exhibits antioxidant properties. β-Tocopherol can inhibit tyrosinase activity and melanin synthesis. β-Tocopherol can also prevent the inhibition of cell growth and of PKC activity caused by d-alpha-tocopherol[1][2][3].
ZK159222, a 25-carboxylic ester analogue of 1α,25-(OH)2D3, is a potent 1α,25-(OH)2D3 receptor (VDR) antagonist. The mechanism of ZK159222 antagonistic action is mediated by a lack of ligand-induced vitaminD receptor interaction with coactivators. ZK159222 has a partial agonistic character .
Thiamine-d3 (hydrochloride) is the deuterium labeled Thiamine hydrochloride. Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.
Riboflavin-d3 is the deuterium labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.
VitaminD3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitaminD. VitaminD3 induces cell differentiation and prevents proliferation of cancer cells.
VitaminD3 octanoate is an octanoate ester of vitaminD3 . VitaminD3 (Cholecalciferol; HY-15398) is a naturally occuring form of vitaminD. VitaminD3 induces cell differentiation and prevents proliferation of cancer cells .
Lumisterol 3 (>90%) (9β,10α-Cholesta-5,7-dien-3β-ol) is a normal human secosterooid metabolite from the class of vitaminD3 photoisomer derivatives. Lumisterol 3 (>90%) is used in the preparation of vitaminD .
7-Dehydrocholesterol (Standard) is the analytical standard of 7-Dehydrocholesterol. This product is intended for research and analytical applications.7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitaminD3.
Secalciferol ((24R)-24,25-Dihydroxyvitamin D3) is the major active metabolite of VitaminD. Secalciferol is involved in a wide range of biological functions such as calcium homeostasis, cellular differentiation and proliferation processes, as well as other functions related to the immune system .
Vitamin D receptor (VDR) protein is the nuclear receptor of calcitriol, which translocates to the nucleus after binding vitamin D3, thereby coordinating cellular activities. VDR forms a heterodimer with RXR, binds to DNA response elements, and initiates the transcription of vitamin D3-responsive genes. Vitamin D Receptor/VDR Protein, Mouse (sf9, His) is the recombinant mouse-derived Vitamin D Receptor/VDR protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of Vitamin D Receptor/VDR Protein, Mouse (sf9, His) is 422 a.a., with molecular weight of ~55 kDa.
Vitamin D receptor (VDR) acts as a nuclear receptor for calcitriol, the active form of vitamin D3, triggering cellular effects. After vitamin D3 binding, VDR translocates to the nucleus and forms a heterodimer with the retinoid X receptor (RXR). Vitamin D Receptor/VDR Protein, Human (sf9, His) is the recombinant human-derived Vitamin D Receptor/VDR protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of Vitamin D Receptor/VDR Protein, Human (sf9, His) is 427 a.a., with molecular weight of ~50 kDa.
UBE2V2 protein lacks independent ubiquitin ligase activity and forms a functional heterodimer with UBE2N. Together, they catalyze nonclassical polyubiquitin chain synthesis ("Lys-63"), distinct from proteasome-driven degradation. UBE2V2 Protein, Human (His) is the recombinant human-derived UBE2V2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of UBE2V2 Protein, Human (His) is 145 a.a., with molecular weight of ~18.0 kDa.
VitaminD3-d7 is the deuterium labeled VitaminD3. VitaminD3 (Cholecalciferol) is a naturally occuring form of vitaminD. VitaminD3 induces cell differentiation and prevents proliferation of cancer cells[1][2].
VitaminD3-d3 is the deuterium labeled VitaminD3. VitaminD3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitaminD. VitaminD3 induces cell differentiation and prevents proliferation of cancer cells.
VitaminD3- 13C3 is the 13C-labeled VitaminD3. VitaminD3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitaminD. VitaminD3 induces cell differentiation and prevents proliferation of cancer cells.
VitaminD3- 13C5 is the deuterium labeled VitaminD3 (HY-15398). VitaminD3 (Cholecalciferol) is a naturally occuring form of vitaminD. VitaminD3 induces cell differentiation and prevents proliferation of cancer cells[1][2].
3-epi-25-Hydroxy VitaminD3-d6is the deuterium labeled3-epi-25-Hydroxy VitaminD3(HY-142140) . 3-epi-25-Hydroxy VitaminD3 is the vitaminD metabolite, while vitaminD metabolism highly dependent on macrophage polarization. The C3-epimerase pathway for vitaminD is active in macrophages .
Calcifediol-d6 (monohydrate) is the deuterium labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy VitaminD3 monohydrate), a major circulating metabolite of vitaminD3, is a potent VDR ligand .
Ercalcidiol-d3 is the deuterium labeled Ercalcidiol. Ercalcidiol is a metabolite of VitaminsD2. Ercalcidiol can be used as an indicator of vitaminsD status .
Calcifediol- 13C5 (monohydrate) is the 13C-labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy VitaminD3 monohydrate), a major circulating metabolite of vitaminD3, is a potent VDR ligand .
Pyridoxine-d3 (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride. Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.
Calcitriol-d3 is the deuterium labeled Calcitriol[1]. Calcitriol is the most active metabolite of vitaminD and also a vitaminD receptor (VDR) agonist[2][3][4][5].
7-Dehydrocholesterol-d7 is the deuterium labeled 7-Dehydrocholesterol. 7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitaminD3[1][2].
Maxacalcitol-d66 is the deuterated form of Maxacalcitol (22-Oxacalcitriol), which is a non-calcemic vitaminD3 analog and VDR ligand of VDR-like receptors.
Methylmalonic acid-d3 is the deuterium labeled Methylmalonic acid. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer[1][2].
L-Tryptophan-d3 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].
Thiamine pyrophosphate-d3 is the deuterium labeled Thiamine pyrophosphate. Thiamine pyrophosphate is the coenzyme form of Vitamin B1 and is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex.
4-Pyridoxic acid-d3 is the deuterium labeled 4-Pyridoxic acid. 4-Pyridoxic acid is a catabolic product of vitamin B6 which is excreted in the urine[1][2].
β-Tocopherol-d3 is the deuterium labeled β-Tocopherol. β-Tocopherol is an analogue of vitamin E, exhibits antioxidant properties. β-Tocopherol can inhibit tyrosinase activity and melanin synthesis. β-Tocopherol can also prevent the inhibition of cell growth and of PKC activity caused by d-alpha-tocopherol[1][2][3].
Thiamine-d3 (hydrochloride) is the deuterium labeled Thiamine hydrochloride. Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.
Riboflavin-d3 is the deuterium labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.
Vitamin D Receptor Antibody is an unconjugated, approximately 47 kDa, rabbit-derived, anti-Vitamin D Receptor polyclonal antibody. Vitamin D Receptor Antibody can be used for: IHC-P, IHC-F, ICC, IF expriments in human, rat, and predicted: mouse, chicken, pig, cow, horse, rabbit background without labeling.